MGC26137, MOG, MYELIN-OLIGODENDROCYTE GLYCOPROTEIN.

Mouse Antibody Monoclonal.

MOG is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. MOG is involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified Minor component of the myelin sheath is involved in completion and/or maintenance of the myelin sheath and in cell- cell communication.

NYRMOG.

synthetic pMOG 35-55.

mouse IgG1.

Ion exchange column.

1mg/ml in PBS (after reconstitution).

Antibody is shipped lyophilized at ambient temperature.

In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC.

Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

By direct ELISA, 1:10,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories).

Direct ELISA, Western Blot, Immuneprecipitation, immunohistochemistry.

Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.