Heat Shock Protein 20, HSP20.

Hsp20 is a mammalian small heat-shock protein family that is found most copiously in skeletal muscle and heart. The heat-shock proteins seem to act as chaperones that can protect other proteins against heat-induced denaturation and aggregation. The Hsp20 family is characterized structurally by the presence of a conserved C-terminal domain of about 100 residues and contains a beta-sandwich fold consisting of 8 strands in 2 beta-sheets in a “Greek-key” topology. Hsp20 proteins have a tendency to form dimers, through a disulphide linkage formed by an N-terminal cysteine, low heat stability and a poor chaperoning ability in comparison with other family members.

Heat Shock Protein 20 Human Recombinant produced in E.Coli.

Escherichia Coli.

Sterile Filtered White lyophilized (freeze-dried) powder.

HSP20 lyophilized from 20mM Tris-acetate, pH-7.6, 10mM NaCl, 0.1mM EDTA, 0.1mM PMSF and 15mM b-mercaptoethanol.

HSP20 although stable at 10°C for 2 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Greater than 95.0% as determined by SDS-PAGE.

Immunoreactivity is confirmed by reaction with monoclonal mouse antibodies against HSP20.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.