Catalogue number
PRO-2094
Synonyms
Dynactin 6, WS3, Dynactin Subunit P27, Protein WS-3, P27,
Novel RGD-Containing Protein, Dynactin Subunit 6, WS-3, Dynactin subunit 6.
Introduction
Dynactin 6, also known as DCTN6 is a member of the dynactin subunits 5/6
family. DCTN6 includes an RGD (Arg-Gly-Asp) motif in the N-terminal region,
which confers adhesive properties to macromolecular proteins such as
fibronectin. DCTN6 has a high degree of sequence resemblance with the mouse
homolog, which has been found to participate in mitochondrial biogenesis.
Moreover, the precise
biological function of DCTN6 is unknown.
Description
DCTN6 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 213 amino acids (1-190 a.a) and
having a molecular mass of 23.1kDa.
DCTN6 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
DCTN6 protein solution (1mg/ml) containing Phosphate
Buffered Saline (pH7.4) and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMAEKTQK SVKIAPGAVV CVESEIRGDV TIGPRTVIHP KARIIAEAGP
IVIGEGNLIE EQALIINAYP DNITPDTEDP EPKPMIIGTN NVFEVGCYSQ AMKMGDNNVI ESKAYVGRNV
ILTSGCIIGA CCNLNTFEVI PENTVIYGAD CLRRVQTERP
QPQTLQLDFL MKILPNYHHL KKTMKGSSTP VKN.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
