Caused by one of four closely related virus serotypes of the genus Flavivirus, family Flaviviridae, each serotype is sufficiently different that there is no cross-protection and epidemics caused by multiple serotypes (hyperendemicity) can occur. In cell culture experiments and mice Morpholino antisense oligos have shown specific activity against Dengue virus.
The E.coli derived recombinant 28 kDa protein is genetically engineered peptide which is derived from Dengue Type-4 Envelope. This region also contains a common antigen for Dengue type 1, 2 and 3.
Escherichia Coli.
Purified by proprietary chromatographic technique.
Protein is >95% pure as determined by 12% PAGE (coomassie staining).
Phosphate buffered saline, pH-7.4.
Dengue Envelope ST4 although stable at 4°C for 1 week, should be stored below -18°C.
Please prevent freeze thaw cycles.
Each laboratory should determine an optimum working titer for use in its particular application.
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