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MMP23B Human

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MMP23B Human


MMP23B Human  的詳細(xì)介紹

Catalogue number

ENZ-793

Synonyms

Matrix Metallopeptidase 23B, MMP23B, MMP22, Matrix Metalloproteinase 23B, Matrix Metalloproteinase 22, Matrix Metalloproteinase In The Female Reproductive Tract, Matrix Metalloproteinase-21, Matrix Metalloproteinase-22, MIFR-1, MMP-21, MMP-22, MMP-23, MIFR, MMP23A, Matrix Metalloproteinase-23, EC 3.4.24.-, Femalysin, MMP21.

Introduction

Matrix Metallopeptidase 23B (MMP23B) belongs to the matrix metalloproteinase (MMP) family, and it is section of a duplicated region of chromosome 1p36.3. MMP23B is a protease. MMP23B regulates the surface expression of some potassium channels by holding them in the endoplasmic reticulum. Members of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis.

Description

MMP23B Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 199 amino acids (79-254) and having a molecular mass of 22.6kDa.
MMP23B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

The MMP23B solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Purity

Greater than 85% as determined by SDS-PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSYTLTPAR LRWDHFNLTY RILSFPRNLL SPRETRRALA AAFRMWSDVS PFSFREVAPE QPSDLRIGFY PINHTDCLVS ALHHCFDGPT GELAHAFFPP HGGIHFDDSE YWVLGPTRYS WKKGVWLTDL VHVAAHEIGH ALGLMHSQHG RALMHLNATL RGWKALSQDE LWGLHRLYG.

Safety Data Sheet

SDS

Usage

Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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