Chromobox Protein Homolog 8 (CBX8) Antibody
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產(chǎn)品名稱: Chromobox Protein Homolog 8 (CBX8) Antibody
產(chǎn)品型號(hào): abx015790
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簡(jiǎn)單介紹
Chromobox Protein Homolog 8 (CBX8) Antibody
Chromobox Protein Homolog 8 (CBX8) Antibody
的詳細(xì)介紹
Chromobox homolog 8 (CBX8), a Polycomb Group protein that interacts with MLL-AF9 and TIP60, plays an essential role in MLL-AF9 transcriptional regulation and leukemogenesis.CBX8, which is part of one of the PRC1 complexes, regulates proliferation of diploid human and mouse fibroblasts through direct binding to the INK4A-ARF locus.
| Target |
CBX8 |
| Reactivity |
Human |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
ELISA, WB, FCM |
| Recommended dilutions |
ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Purified recombinant fragment of human CBX8 (AA: 17-222) expressed in E. coli. |
| Purification |
Purified antibody |
| Isotype |
IgG1 |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
43.4 kDa |
| Swiss Prot |
Q9HC52
|
| GeneID |
57332
|
| Gene Symbol |
CBX8 |
| OMIM |
617354
|
| HGNC |
15962 |
| Ensembl |
ENSG00000141570 |
| Concentration |
1.0 mg/ml |
| Buffer |
PBS with 0.05% sodium azide and 0.5% protein stabilizer. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
