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產(chǎn)品名稱: CD57 Antibody (FITC)
產(chǎn)品型號: abx200385
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關文檔
簡單介紹
CD57 Antibody (FITC)
的詳細介紹
This antibody reacts with a carbohydrate antigen present on a subset of peripheral blood mononuclear cells involved in the Natural Killer activity, which is not MHC restricted. The antigen is not present on B cells, monocytes, red blood cells or platelets but is expressed on cells in neuroectodermal tissue. It reacts with 20% of normal human peripheral blood mononuclear cells.
Target |
CD57 |
Reactivity |
Human |
Host |
Mouse |
Clonality |
Monoclonal |
Tested Applications |
FCM |
Recommended dilutions |
FCM: 20 μl/1 million cells. Optimal dilutions/concentrations should be determined by the end user. |
Immunogen |
Human neuroblastoma cells. |
Purification |
Affinity Chromatography |
Form |
Liquid |
Isotype |
IgM |
Conjugation |
FITC |
Specificity |
CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants). |
Storage |
Store in the dark at 2-8 °C. |
Molecular Weight |
110 kDa |
Swiss Prot |
Q96E93
|
GeneID |
27087
|
Buffer |
The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide |
UNSPSC Code |
12352203 |
Availability |
Shipped within 3-5 working days. |
Note |
This product is for research use only. |