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產(chǎn)品名稱: CD42b Antibody (Biotin)
產(chǎn)品型號(hào): abx200282
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
CD42b Antibody (Biotin)
的詳細(xì)介紹
The antibody is directed against the CD42b antigen, platelet glycoprotein gp1bA, that serves as a receptor for Von Willebrand factor (vWF) and as a high affinity thrombin receptor. AK2 immunblots a band of 130kDa on SDS gels of platelet lysates and gives surface immunofluorescence with fixed or unfixed platelets. The antigen is absent in very low levels on platelets with the Bernard-Soulier syndrome
| Target |
CD42b |
| Reactivity |
Human, Monkey |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
FCM |
| Recommended dilutions |
FCM: 20 μl/1 million cells. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Tissue / cell preparation (Human). Peripheral blood mononuclear cells of a patient suffering with CLL. |
| Purification |
Affinity Chromatography |
| Form |
Liquid |
| Isotype |
IgG1 |
| Conjugation |
Biotin |
| Specificity |
CD42b is a 145 kD glycoprotein known as gpIbα. It is composed in a heterodimer with a b chain (CD42c, gpIbb) through a disulfide bond. CD42b is expressed on platelets and megakaryocytes. CD42b/c heterodimer forms a complex with CD42a and d and acts as the receptor for Von Willibrand factor and thrombin. |
| Storage |
Store in the dark at 2-8 °C. |
| Molecular Weight |
17-22kDa |
| Swiss Prot |
P07359
|
| GeneID |
2812
|
| Buffer |
The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 2-3 weeks. |
| Note |
This product is for research use only. |
