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產(chǎn)品名稱: CD35 Antibody (FITC)
產(chǎn)品型號: abx200241
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
CD35 Antibody (FITC)
的詳細(xì)介紹
CD35 is also known as C3b/C4b receptor or CR1. Four molecular weight allotypes (160kD,190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells,erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b,C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediatingphagocytosis by granulocytes and monocytes.
| Target |
CD35 |
| Reactivity |
Human |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
FCM |
| Recommended dilutions |
FCM: 20 μl/1 million cells. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Human Cells of the Monocyte Lineage. |
| Purification |
Affinity Chromatography |
| Form |
Liquid |
| Isotype |
IgG1 |
| Conjugation |
FITC |
| Specificity |
Reacts with CR1, the receptor for the complement component C3b, composed of four different allotypes (160, 190, 220 and 250 kD). CD35 antigen is expressed on granulocytes, monocytes, B cells, some NK cells and erythrocytes. It binds complement components C3b and C4b, mediating phagocytosis by neutrophils and monocytes. This antibody cannot inhibit the phagocytic capacity of granulocytes. CD35 antibody is useful in studies of complement receptors. |
| Storage |
Store in the dark at 2-8 °C. |
| Molecular Weight |
280 kDa |
| Swiss Prot |
P17927
|
| GeneID |
1378
|
| Buffer |
The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 3-5 working days. |
| Note |
This product is for research use only. |
