Catenin Beta 1 (CTNNB1) Antibody
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產(chǎn)品名稱: Catenin Beta 1 (CTNNB1) Antibody
產(chǎn)品型號: abx025451
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Catenin Beta 1 (CTNNB1) Antibody
的詳細介紹
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene. This antibody is supplied as crude ascites.
| Target |
CTNNB1 |
| Reactivity |
Human |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
WB |
| Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Human CTNNB1. |
| Purification |
Mouse Monoclonal Antibody (Mab) supplied as crude ascites. |
| Isotype |
IgM |
| Conjugation |
Unconjugated |
| Specificity |
This CTNNB1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 646-673 amino acids from human CTNNB1. |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
P35222
|
| Buffer |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
