Caspase 14 (CASP14) Antibody
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產(chǎn)品名稱: Caspase 14 (CASP14) Antibody
產(chǎn)品型號: abx005020
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Caspase 14 (CASP14) Antibody
的詳細(xì)介紹
CASP14 Antibody is a Rabbit Polyclonal antibody against CASP14. This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.
| Target |
CASP14 |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, IF/ICC |
| Recommended dilutions |
WB: 1/500 - 1/2000, IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human CASP14. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 27 kDa
Observed MW: 30 kDa |
| Swiss Prot |
P31944
|
| GeneID |
23581
|
| Gene Symbol |
CASP14 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
