Carcinoembryonic Antigen Related Cell Adhesion Molecule 1 (CEACAM1) Antibody
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產(chǎn)品名稱: Carcinoembryonic Antigen Related Cell Adhesion Molecule 1 (CEACAM1) Antibody
產(chǎn)品型號: abx001427
產(chǎn)品展商: 其他品牌
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簡單介紹
Carcinoembryonic Antigen Related Cell Adhesion Molecule 1 (CEACAM1) Antibody
Carcinoembryonic Antigen Related Cell Adhesion Molecule 1 (CEACAM1) Antibody
的詳細介紹
CEACAM1 Antibody is a Rabbit Polyclonal antibody against CEACAM1. This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.
| Target |
CEACAM1 |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human CEACAM1. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 27 kDa/35-57 kDa
Observed MW: 58 kDa |
| Swiss Prot |
P13688
|
| GeneID |
634
|
| Gene Symbol |
CEACAM1 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
