Calpain-6 (CAPN6) Antibody
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產品名稱: Calpain-6 (CAPN6) Antibody
產品型號: abx002726
產品展商: 其他品牌
產品文檔: 無相關文檔
簡單介紹
Calpain-6 (CAPN6) Antibody
的詳細介紹
CAPN6 Antibody is a Rabbit Polyclonal antibody against CAPN6. Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.
| Target |
CAPN6 |
| Reactivity |
Human, Mouse |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human CAPN6. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Store at 4 °C. |
| Molecular Weight |
Calculated MW: 74 kDa
Observed MW: 71 kDa |
| Swiss Prot |
Q9Y6Q1
|
| GeneID |
827
|
| Gene Symbol |
CAPN6 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
