Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1B (PDE1
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產(chǎn)品名稱: Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1B (PDE1
產(chǎn)品型號(hào): abx015961
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1B (PDE1B) Antibody
Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1B (PDE1
的詳細(xì)介紹
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily.Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex.This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate.cAMP and cGMP function as key regulators of many important physiological processes.Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Target |
PDE1B |
Reactivity |
Human, Mouse, Monkey |
Host |
Mouse |
Clonality |
Monoclonal |
Tested Applications |
ELISA, WB, FCM |
Recommended dilutions |
ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
Immunogen |
Purified recombinant fragment of human PDE1B (AA: 370-536) expressed in E. coli. |
Purification |
Purified antibody |
Isotype |
IgG1 |
Conjugation |
Unconjugated |
Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
Molecular Weight |
61.4 kDa |
GeneID |
5153
|
Concentration |
1.0 mg/ml |
Buffer |
PBS with 0.05% sodium azide and 0.5% protein stabilizer. |
UNSPSC Code |
12352203 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |