Calcipressin-1 (RCAN1) Antibody
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產(chǎn)品名稱(chēng): Calcipressin-1 (RCAN1) Antibody
產(chǎn)品型號(hào): abx004072
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
Calcipressin-1 (RCAN1) Antibody
的詳細(xì)介紹
RCAN1 Antibody is a Rabbit Polyclonal antibody against RCAN1. The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.
| Target |
RCAN1 |
| Reactivity |
Human, Mouse |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, IHC, IF/ICC |
| Recommended dilutions |
WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human RCAN1. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 13 kDa/19 kDa/22 kDa/28 kDa
Observed MW: 31 kDa |
| Swiss Prot |
P53805
|
| GeneID |
1827
|
| Gene Symbol |
RCAN1 |
| Concentration |
1.79 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
