Cadherin-5/VE-Cadherin (Vascular Endothelial) (CDH5) Antibody
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產(chǎn)品名稱: Cadherin-5/VE-Cadherin (Vascular Endothelial) (CDH5) Antibody
產(chǎn)品型號: abx000842
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Cadherin-5/VE-Cadherin (Vascular Endothelial) (CDH5) Antibody
Cadherin-5/VE-Cadherin (Vascular Endothelial) (CDH5) Antibody
的詳細(xì)介紹
CDH5 Antibody is a Rabbit Polyclonal antibody against CDH5. This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.
| Target |
CDH5 |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
A synthetic peptide of human CDH5. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 74 kDa/87 kDa
Observed MW: 120 kDa |
| Swiss Prot |
P33151
|
| GeneID |
1003
|
| Gene Symbol |
CDH5 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
