Cadherin 1 (CDH1) Antibody
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產(chǎn)品名稱: Cadherin 1 (CDH1) Antibody
產(chǎn)品型號: abx034792
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Cadherin 1 (CDH1) Antibody
的詳細(xì)介紹
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
| Target |
CDH1 |
| Reactivity |
Human, Mouse |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
WB, IHC |
| Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
| Purification |
Purified Mouse Monoclonal Antibody. |
| Isotype |
IgG1κ |
| Conjugation |
Unconjugated |
| Specificity |
Purified His-tagged CDH1 protein was used to produced this monoclonal antibody. |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
P12830
|
| NCBI Accession |
NP_004351.1
|
| Buffer |
PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
