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產(chǎn)品名稱: C-RAF (pS621) Antibody
產(chǎn)品型號: abx011442
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
C-RAF (pS621) Antibody
的詳細(xì)介紹
Phospho-C-RAF (Ser621) Antibody detects endogenous levels of C-RAF only when phosphorylated at Serine 621. Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn
| Target |
C-RAF (pS621) |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
| Purification |
Purified by affinity chromatography. |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
P04049
|
| GeneID |
5894
|
| Gene Symbol |
RAF1 |
| OMIM |
164760
|
| Enzyme Commission Number |
EC 2.7.11.1 |
| HGNC |
9829 |
| Ensembl |
ENSG00000132155 |
| Buffer |
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
