Breast Cancer-Specific Gene 1 Protein (SNCG) Antibody
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產品名稱: Breast Cancer-Specific Gene 1 Protein (SNCG) Antibody
產品型號: abx011543
產品展商: 其他品牌
產品文檔: 無相關文檔
簡單介紹
Breast Cancer-Specific Gene 1 Protein (SNCG) Antibody
Breast Cancer-Specific Gene 1 Protein (SNCG) Antibody
的詳細介紹
SNCG (also designated gamma synuclein or breast cancer-specific protein 1),with 127-amino acid protein (about 14kDa), belongs to the synuclein family, which also includes alpha and beta synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.
Target |
SNCG (breast cancer-specific protein 1) |
Reactivity |
Human |
Host |
Mouse |
Clonality |
Monoclonal |
Tested Applications |
ELISA, WB, IHC |
Recommended dilutions |
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Immunogen |
Purified recombinant fragment of SNCG expressed in E. Coli. |
Purification |
Purified antibody |
Isotype |
IgG1 |
Conjugation |
Unconjugated |
Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
Molecular Weight |
13 kDa |
Swiss Prot |
O76070
|
GeneID |
6623
|
Gene Symbol |
SNCG |
OMIM |
602998
|
HGNC |
11141 |
Ensembl |
ENSG00000173267 |
Concentration |
1.0 mg/ml |
Buffer |
PBS containing 0.03% sodium azide. |
UNSPSC Code |
12352203 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |