Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2 (BAIAP2) Antibody
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產(chǎn)品名稱: Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2 (BAIAP2) Antibody
產(chǎn)品型號(hào): abx004080
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Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2 (BAIAP2) Antibody
Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2 (BAIAP2) Antibody
的詳細(xì)介紹
BAIAP2 Antibody is a Rabbit Polyclonal antibody against BAIAP2. The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Target |
Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2 (BAIAP2) |
Reactivity |
Human, Rat |
Host |
Rabbit |
Clonality |
Polyclonal |
Tested Applications |
WB, IHC, IF/ICC |
Recommended dilutions |
WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Immunogen |
Recombinant protein of human BAIAP2. |
Purification |
Affinity purified. |
Form |
Liquid |
Isotype |
IgG |
Conjugation |
Unconjugated |
Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
Molecular Weight |
Calculated MW: 56 kDa/57 kDa/59 kDa/60 kDa Observed MW: 65 kDa |
Swiss Prot |
Q9UQB8
|
GeneID |
10458
|
Gene Symbol |
BAIAP2 |
Concentration |
> 1 mg/ml |
Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
UNSPSC Code |
12352203 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |