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產(chǎn)品名稱: BRAF (pS445) Antibody
產(chǎn)品型號: abx031977
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
BRAF (pS445) Antibody
的詳細(xì)介紹
BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neuron. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer.
Target |
BRAF (pS445) |
Reactivity |
Human |
Host |
Rabbit |
Clonality |
Polyclonal |
Tested Applications |
DB |
Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
Immunogen |
Human BRAF (phospho-Ser445). |
Purification |
Peptide Affinity Purified Rabbit Polyclonal Antibody. |
Isotype |
IgG |
Conjugation |
Unconjugated |
Specificity |
This BRAF Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S445 of human BRAF. |
Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
Swiss Prot |
P15056
|
Buffer |
PBS with 0.09% (W/V) sodium azide. This antibody is first purified by protein A affinity chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
UNSPSC Code |
12352203 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |