Bone Morphogenetic Protein Receptor 2 (BMPR2) Antibody
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產(chǎn)品名稱: Bone Morphogenetic Protein Receptor 2 (BMPR2) Antibody
產(chǎn)品型號: abx015778
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Bone Morphogenetic Protein Receptor 2 (BMPR2) Antibody
Bone Morphogenetic Protein Receptor 2 (BMPR2) Antibody
的詳細(xì)介紹
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases.The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily.BMPs are involved in endochondral bone formation and embryogenesis.These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD.Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. (provided by RefSeq).
| Target |
BMPR2 |
| Reactivity |
Human, Mouse, Rat, Monkey |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
ELISA, WB, IHC, IF/ICC |
| Recommended dilutions |
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Purified recombinant fragment of human BMPR2 expressed in E. coli. |
| Purification |
Unpurified Ascites. |
| Isotype |
IgG1 |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
115 kDa |
| GeneID |
659
|
| Buffer |
Ascitic fluid containing 0.03% sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
