Bone Morphogenetic Protein 4 (BMP4) Antibody
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產(chǎn)品名稱: Bone Morphogenetic Protein 4 (BMP4) Antibody
產(chǎn)品型號(hào): abx011757
產(chǎn)品展商: 其他品牌
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Bone Morphogenetic Protein 4 (BMP4) Antibody
Bone Morphogenetic Protein 4 (BMP4) Antibody
的詳細(xì)介紹
The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor beta superfamily. The superfamily includes large families of growth and differentiation factors.BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.
| Target |
BMP4 |
| Reactivity |
Human |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
ELISA, WB |
| Recommended dilutions |
ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Purified recombinant fragment of human BMP4 expressed in E. Coli. |
| Purification |
Unpurified Ascites. |
| Isotype |
IgG1 |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
64 kDa |
| Swiss Prot |
P12644
|
| GeneID |
652
|
| Gene Symbol |
BMP4 |
| OMIM |
112262
|
| HGNC |
1071 |
| Ensembl |
ENSG00000125378 |
| Buffer |
Ascitic fluid containing 0.03% sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
