BH3-Interacting Domain Death Agonist (BID) Antibody
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產(chǎn)品名稱: BH3-Interacting Domain Death Agonist (BID) Antibody
產(chǎn)品型號(hào): abx011976
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BH3-Interacting Domain Death Agonist (BID) Antibody
BH3-Interacting Domain Death Agonist (BID) Antibody
的詳細(xì)介紹
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
| Target |
BID |
| Reactivity |
Human |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
ELISA, WB, IHC, IF/ICC, FCM |
| Recommended dilutions |
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Purified recombinant fragment of human BID expressed in E. Coli. |
| Purification |
Unpurified Ascites. |
| Isotype |
IgG1 |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
22 kDa |
| Swiss Prot |
P55957
|
| GeneID |
637
|
| Gene Symbol |
BID |
| OMIM |
601997
|
| HGNC |
1050 |
| Ensembl |
ENSG00000015475 |
| Buffer |
Ascitic fluid containing 0.03% sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
