Beta-Site APP Cleaving Enzyme 1 (BACE1) Antibody
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產(chǎn)品名稱: Beta-Site APP Cleaving Enzyme 1 (BACE1) Antibody
產(chǎn)品型號: abx033674
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Beta-Site APP Cleaving Enzyme 1 (BACE1) Antibody
Beta-Site APP Cleaving Enzyme 1 (BACE1) Antibody
的詳細(xì)介紹
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
Target |
Beta-Site APP Cleaving Enzyme 1 (BACE1) |
Reactivity |
Human, Mouse |
Host |
Rabbit |
Clonality |
Polyclonal |
Tested Applications |
WB, IHC |
Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
Immunogen |
Human BACE1. |
Purification |
Purified Rabbit Polyclonal Antibody. |
Isotype |
IgG |
Conjugation |
Unconjugated |
Specificity |
This BACE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-70 amino acids from the N-terminal region of human BACE1. |
Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
Swiss Prot |
P56817
|
NCBI Accession |
NP_001193978.1
NP_036236.1
NP_620427.1
NP_620428.1
NP_620429.1
|
Buffer |
PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
UNSPSC Code |
12352203 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |