Beta-Site APP Cleaving Enzyme 1 (BACE1) Antibody
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產(chǎn)品名稱: Beta-Site APP Cleaving Enzyme 1 (BACE1) Antibody
產(chǎn)品型號(hào): abx005456
產(chǎn)品展商: 其他品牌
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Beta-Site APP Cleaving Enzyme 1 (BACE1) Antibody
Beta-Site APP Cleaving Enzyme 1 (BACE1) Antibody
的詳細(xì)介紹
bACE1 Antibody is a Rabbit Polyclonal antibody against bACE1. Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene.
| Target |
Beta-Site APP Cleaving Enzyme 1 (BACE1) |
| Reactivity |
Human, Mouse, Zebrafish |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, IHC, IP |
| Recommended dilutions |
WB: 1/200 - 1/2000, IHC: 1/50 - 1/200, IP: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human BACE1. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 42 kDa/45 kDa/48 kDa/51 kDa/52 kDa/55 kDa
Observed MW: 80 kDa |
| Swiss Prot |
P56817
|
| GeneID |
23621
|
| Gene Symbol |
BACE1 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
