Bcl2-Related?protein?A1 (BCL2A1) Antibody
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產(chǎn)品名稱: Bcl2-Related?protein?A1 (BCL2A1) Antibody
產(chǎn)品型號(hào): abx000565
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Bcl2-Related?protein?A1 (BCL2A1) Antibody
Bcl2-Related?protein?A1 (BCL2A1) Antibody
的詳細(xì)介紹
BCL2A1 Antibody is a Rabbit Polyclonal antibody against BCL2A1. This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Target |
BCL2A1 |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, IHC, FCM |
| Recommended dilutions |
WB: 1/500 - 1/1000, IHC: 1/20 - 1/50, FCM: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human BCL2A1. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Store at 4 °C. |
| Molecular Weight |
Calculated MW: 18 kDa/20 kDa
Observed MW: 20 kDa |
| Swiss Prot |
Q16548
|
| GeneID |
597
|
| Gene Symbol |
BCL2A1 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
