Bcl2-Binding Component 3 (BBC3) Antibody
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產(chǎn)品名稱(chēng): Bcl2-Binding Component 3 (BBC3) Antibody
產(chǎn)品型號(hào): abx002105
產(chǎn)品展商: 其他品牌
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Bcl2-Binding Component 3 (BBC3) Antibody
Bcl2-Binding Component 3 (BBC3) Antibody
的詳細(xì)介紹
BBC3 Antibody is a Rabbit Polyclonal antibody against BBC3. This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.
| Target |
BBC3 |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
A synthetic peptide of human BBC3. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 10 kDa/14 kDa/20 kDa/26 kDa
Observed MW: 23 kDa |
| Swiss Prot |
Q9BXH1
|
| GeneID |
27113
|
| Gene Symbol |
BBC3 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
