BCL2-Antagonist/Killer 1 (BAK1) Antibody
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產(chǎn)品名稱: BCL2-Antagonist/Killer 1 (BAK1) Antibody
產(chǎn)品型號: abx000593
產(chǎn)品展商: 其他品牌
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簡單介紹
BCL2-Antagonist/Killer 1 (BAK1) Antibody
BCL2-Antagonist/Killer 1 (BAK1) Antibody
的詳細(xì)介紹
BAK1 Antibody is a Rabbit Polyclonal antibody against BAK1. The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
| Target |
BAK1 |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, IF/ICC |
| Recommended dilutions |
WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Synthetic peptide. N term -peptide of human BAK1. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 16 kDa/23 kDa
Observed MW: 26 kDa |
| Swiss Prot |
Q16611
|
| GeneID |
578
|
| Gene Symbol |
Bak1 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
