Bcl2 Associated Athanogene 3 (BAG3) Antibody
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產(chǎn)品名稱: Bcl2 Associated Athanogene 3 (BAG3) Antibody
產(chǎn)品型號: abx005532
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Bcl2 Associated Athanogene 3 (BAG3) Antibody
Bcl2 Associated Athanogene 3 (BAG3) Antibody
的詳細介紹
BAG3 Antibody is a Rabbit Polyclonal antibody against BAG3. BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
| Target |
BAG3 |
| Reactivity |
Human |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human BAG3. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Store at 4 °C. |
| Molecular Weight |
Calculated MW: 61 kDa
Observed MW: 70 kDa |
| Swiss Prot |
O95817
|
| GeneID |
9531
|
| Gene Symbol |
BAG3 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
