Bcl2 Associated X Protein (BAX) Antibody
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產(chǎn)品名稱: Bcl2 Associated X Protein (BAX) Antibody
產(chǎn)品型號: abx001820
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Bcl2 Associated X Protein (BAX) Antibody
Bcl2 Associated X Protein (BAX) Antibody
的詳細介紹
BAX Antibody is a Rabbit Polyclonal antibody against BAX. The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
| Target |
BAX |
| Reactivity |
Human, Monkey |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant fusion protein of human Bax. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 4 kDa/12 kDa/15 kDa/18 kDa/19 kDa/21 kDa/24 kDa
Observed MW: 21 kDa |
| Swiss Prot |
Q07812
|
| GeneID |
581
|
| Gene Symbol |
BAX |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
