Bcl-2-Like Protein 1 (BCL2L1) Antibody
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產(chǎn)品名稱: Bcl-2-Like Protein 1 (BCL2L1) Antibody
產(chǎn)品型號: abx000597
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關文檔
簡單介紹
Bcl-2-Like Protein 1 (BCL2L1) Antibody
的詳細介紹
BCL2L1 Antibody is a Rabbit Polyclonal antibody against BCL2L1. The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq].
| Target |
BCL2L1 |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human BCL2L1. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 18 kDa/25-26 kDa
Observed MW: 30 kDa |
| Swiss Prot |
Q07817
|
| GeneID |
598
|
| Gene Symbol |
BCL2L1 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
