B-Lymphocyte Antigen CD20 (CD20) Antibody
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產(chǎn)品名稱: B-Lymphocyte Antigen CD20 (CD20) Antibody
產(chǎn)品型號(hào): abx010519
產(chǎn)品展商: 其他品牌
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簡單介紹
B-Lymphocyte Antigen CD20 (CD20) Antibody
B-Lymphocyte Antigen CD20 (CD20) Antibody
的詳細(xì)介紹
CD20 (MS4A1, membrane-spanning 4-domains, subfamily A, member 1) is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. And it is known to accelerate the G0 to G1 progression induced by IGF-1.
| Target |
CD20 |
| Reactivity |
Human |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
ELISA, IHC, IF/ICC |
| Recommended dilutions |
ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Synthetic peptide corresponding to aa (EPANPSEKNSPSTQY) of human CD20,conjugated to KLH. |
| Purification |
Unpurified Ascites. |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
33 kDa |
| Swiss Prot |
P11836
|
| GeneID |
931
|
| Gene Symbol |
MS4A1 |
| OMIM |
112210
|
| HGNC |
7315 |
| Ensembl |
ENSG00000156738 |
| Buffer |
Ascitic fluid containing 0.03% sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
