B-Cell Linker Protein (BLNK) Antibody
如果您對該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱: B-Cell Linker Protein (BLNK) Antibody
產(chǎn)品型號: abx025447
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
B-Cell Linker Protein (BLNK) Antibody
的詳細介紹
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. This antibody is supplied as crude ascites.
| Target |
BLNK |
| Reactivity |
Human |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
WB |
| Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Human BLNK. |
| Purification |
Mouse Monoclonal Antibody (Mab) supplied as crude ascites. |
| Isotype |
IgM |
| Conjugation |
Unconjugated |
| Specificity |
This BLNK antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 150-178 amino acids from human BLNK. |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
Q8WV28
|
| Buffer |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
