B-Cell CLL/Lymphoma 6 (BCL6) Antibody
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產品名稱: B-Cell CLL/Lymphoma 6 (BCL6) Antibody
產品型號: abx025320
產品展商: 其他品牌
產品文檔: 無相關文檔
簡單介紹
B-Cell CLL/Lymphoma 6 (BCL6) Antibody
的詳細介紹
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. This antibody is supplied as crude ascites.
Target |
BCL6 |
Reactivity |
Human |
Host |
Mouse |
Clonality |
Monoclonal |
Tested Applications |
WB, IF/ICC |
Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
Immunogen |
Human BCL6. |
Purification |
Mouse Monoclonal Antibody (Mab) supplied as crude ascites. |
Isotype |
IgG1 |
Conjugation |
Unconjugated |
Specificity |
This BCL6 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 676-704 amino acids from the C-terminal region of human BCL6. |
Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
Swiss Prot |
P41182
|
Buffer |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
UNSPSC Code |
12352203 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |