ATP Binding Cassette Transporter G5 (ABCG5) Antibody
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產(chǎn)品名稱(chēng): ATP Binding Cassette Transporter G5 (ABCG5) Antibody
產(chǎn)品型號(hào): abx015758
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ATP Binding Cassette Transporter G5 (ABCG5) Antibody
ATP Binding Cassette Transporter G5 (ABCG5) Antibody
的詳細(xì)介紹
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).This protein is a member of the White subfamily.The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols.It is expressed in a tissue-specific manner in the liver, colon, and intestine.This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8.Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.
| Target |
ABCG5 |
| Reactivity |
Human |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
ELISA, WB, FCM |
| Recommended dilutions |
ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Purified recombinant fragment of human ABCG5 (AA: 306-367) expressed in E. coli. |
| Purification |
Purified antibody |
| Isotype |
IgG1 |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
72.5 kDa |
| Concentration |
1.0 mg/ml |
| Buffer |
PBS with 0.05% sodium azide and 0.5% protein stabilizer. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
