ATP Binding Cassette Transporter C5 (ABCC5) Antibody
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產(chǎn)品名稱: ATP Binding Cassette Transporter C5 (ABCC5) Antibody
產(chǎn)品型號: abx002191
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關文檔
簡單介紹
ATP Binding Cassette Transporter C5 (ABCC5) Antibody
ATP Binding Cassette Transporter C5 (ABCC5) Antibody
的詳細介紹
ABCC5 Antibody is a Rabbit Polyclonal antibody against ABCC5. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine.
| Target |
ABCC5 |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
A synthetic peptide of human ABCC5. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 23 kDa/25 kDa/155 kDa/160 kDa
Observed MW: 185 kDa |
| Swiss Prot |
O15440
|
| GeneID |
10057
|
| Gene Symbol |
ABCC5 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
