ATP Binding Cassette Transporter A1 (ABCA1) Antibody
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產(chǎn)品名稱: ATP Binding Cassette Transporter A1 (ABCA1) Antibody
產(chǎn)品型號(hào): abx005455
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ATP Binding Cassette Transporter A1 (ABCA1) Antibody
ATP Binding Cassette Transporter A1 (ABCA1) Antibody
的詳細(xì)介紹
ABCA1 Antibody is a Rabbit Polyclonal antibody against ABCA1. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.
| Target |
ATP Binding Cassette Transporter A1 (ABCA1) |
| Reactivity |
Human, Mouse |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
A synthetic peptide of human ABCA1. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 254 kDa
Observed MW: 254 kDa |
| Swiss Prot |
O95477
|
| GeneID |
19
|
| Gene Symbol |
ABCA1 |
| OMIM |
600046
|
| HGNC |
29 |
| Ensembl |
ENSG00000165029 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
