Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Antibody
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產(chǎn)品名稱: Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Antibody
產(chǎn)品型號: abx000925
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關文檔
簡單介紹
Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Antibody
Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Antibody
的詳細介紹
ARNT Antibody is a Rabbit Polyclonal antibody against ARNT. This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants.
| Target |
ARNT |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human ARNT. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 84 kDa/85 kDa/86 kDa
Observed MW: 87 kDa |
| Swiss Prot |
P27540
|
| GeneID |
405
|
| Gene Symbol |
ARNT |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
