Aryl Hydrocarbon Receptor (AHR) Antibody
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產(chǎn)品名稱(chēng): Aryl Hydrocarbon Receptor (AHR) Antibody
產(chǎn)品型號(hào): abx001244
產(chǎn)品展商: 其他品牌
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Aryl Hydrocarbon Receptor (AHR) Antibody
Aryl Hydrocarbon Receptor (AHR) Antibody
的詳細(xì)介紹
AHR Antibody is a Rabbit Polyclonal antibody against AHR. The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that has been largely regarded as a mediator of xenobiotic metabolism [PMID:18483242]. It plays a part role in physiologic activities, including attenuation of the acute phase response, cytokine signaling, T helper (TH)17 immune cell differentiation, modulation of NF-κB activity, and regulation of hormonal signaling [PMID:20423157,18540824]. It also mediates transcription factor sequestering away from a gene promoter or tethering of the AhR to a transcription factor on a promoter.
Target |
AHR |
Reactivity |
Human, Mouse, Rat |
Host |
Rabbit |
Clonality |
Polyclonal |
Tested Applications |
WB, IHC |
Recommended dilutions |
WB: 1/200 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Immunogen |
Recombinant protein of human AHR. |
Purification |
Affinity purified. |
Form |
Liquid |
Isotype |
IgG |
Conjugation |
Unconjugated |
Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
Molecular Weight |
Calculated MW: 96 kDa Observed MW: 115 kDa |
Swiss Prot |
P35869
|
GeneID |
196
|
Gene Symbol |
AHR |
Concentration |
> 1 mg/ml |
Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
UNSPSC Code |
12352203 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |