Apoptosis Inducing Factor 1, Mitochondrial (AIFM1) Antibody
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產(chǎn)品名稱: Apoptosis Inducing Factor 1, Mitochondrial (AIFM1) Antibody
產(chǎn)品型號: abx002005
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關文檔
簡單介紹
Apoptosis Inducing Factor 1, Mitochondrial (AIFM1) Antibody
Apoptosis Inducing Factor 1, Mitochondrial (AIFM1) Antibody
的詳細介紹
AIFM1 Antibody is a Rabbit Polyclonal antibody against AIFM1. This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.
| Target |
AIFM1 |
| Reactivity |
Human, Mouse |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, IHC, IF/ICC |
| Recommended dilutions |
WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human AIFM1. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 26 kDa/28 kDa/35 kDa/66 kDa
Observed MW: 67 kDa |
| Swiss Prot |
O95831
|
| GeneID |
9131
|
| Gene Symbol |
AIFM1 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
