Apolipoprotein B (APOB) Antibody
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產(chǎn)品名稱: Apolipoprotein B (APOB) Antibody
產(chǎn)品型號(hào): abx000052
產(chǎn)品展商: 其他品牌
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Apolipoprotein B (APOB) Antibody
的詳細(xì)介紹
APOB Antibody is a Mouse Monoclonal antibody against APOB. This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.
| Target |
APOB |
| Reactivity |
Human |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
WB, IF/ICC, FCM |
| Recommended dilutions |
WB: 1/500 - 1/2000, IF/ICC: 1/500 - 1/1000, FCM: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human APOB. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 515 kDa
Observed MW: 45 kDa |
| Swiss Prot |
P04114
|
| GeneID |
338
|
| Gene Symbol |
APOB |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
