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產(chǎn)品名稱: Apoa5 (bd) Antibody
產(chǎn)品型號: abx015771
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Apoa5 (bd) Antibody
的詳細介紹
Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations.An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglyc erides, whereas a knock-in model with human ApoA5 produced 50–70% lower concentrations of mouse serum triglycerides.In addition, peroxisome proliferator-activated receptor-_ agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression.Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.
| Target |
Apoa5 (bd) |
| Reactivity |
Human |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
ELISA |
| Recommended dilutions |
ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Purified recombinant fragment of human APOA5 (AA: 180-363) expressed in E. coli. |
| Purification |
Unpurified Ascites. |
| Isotype |
IgG1 |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
41.2 kDa |
| Swiss Prot |
Q6Q788
|
| GeneID |
116519
|
| Gene Symbol |
APOA5 |
| OMIM |
606368
|
| HGNC |
17288 |
| Ensembl |
ENSG00000110243 |
| Buffer |
Ascitic fluid containing 0.03% sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
