Angiopoietin Like Protein 3 (ANGPTL3) Antibody
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產(chǎn)品名稱: Angiopoietin Like Protein 3 (ANGPTL3) Antibody
產(chǎn)品型號(hào): abx000824
產(chǎn)品展商: 其他品牌
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簡單介紹
Angiopoietin Like Protein 3 (ANGPTL3) Antibody
Angiopoietin Like Protein 3 (ANGPTL3) Antibody
的詳細(xì)介紹
ANGPTL3 Antibody is a Rabbit Polyclonal antibody against ANGPTL3. Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?(v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes.
Target |
ANGPTL3 |
Reactivity |
Human, Mouse, Rat |
Host |
Rabbit |
Clonality |
Polyclonal |
Tested Applications |
WB, IHC |
Recommended dilutions |
WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Immunogen |
Recombinant protein of human ANGPTL3. |
Purification |
Affinity purified. |
Form |
Liquid |
Isotype |
IgG |
Conjugation |
Unconjugated |
Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
Molecular Weight |
Calculated MW: 53 kDa Observed MW: 53 kDa |
Swiss Prot |
Q9Y5C1
|
GeneID |
27329
|
Gene Symbol |
ANGPTL3 |
Concentration |
> 1 mg/ml |
Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
UNSPSC Code |
12352203 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |