Anaphase Promoting Complex Subunit 5 (ANAPC5) Antibody
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產品名稱: Anaphase Promoting Complex Subunit 5 (ANAPC5) Antibody
產品型號: abx003579
產品展商: 其他品牌
產品文檔: 無相關文檔
簡單介紹
Anaphase Promoting Complex Subunit 5 (ANAPC5) Antibody
Anaphase Promoting Complex Subunit 5 (ANAPC5) Antibody
的詳細介紹
ANAPC5 Antibody is a Rabbit Polyclonal antibody against ANAPC5. This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.
| Target |
ANAPC5 |
| Reactivity |
Human |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, FCM |
| Recommended dilutions |
WB: 1/500 - 1/1000, FCM: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human ANAPC5. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Store at 4 °C. |
| Molecular Weight |
Calculated MW: 25 kDa/72 kDa/85 kDa
Observed MW: 85 kDa |
| Swiss Prot |
Q9UJX4
|
| GeneID |
51433
|
| Gene Symbol |
ANAPC5 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
