Amyloid Beta Precursor Like Protein 2 (APLP2) Antibody
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產(chǎn)品名稱: Amyloid Beta Precursor Like Protein 2 (APLP2) Antibody
產(chǎn)品型號: abx004176
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關文檔
簡單介紹
Amyloid Beta Precursor Like Protein 2 (APLP2) Antibody
Amyloid Beta Precursor Like Protein 2 (APLP2) Antibody
的詳細介紹
APLP2 Antibody is a Rabbit Polyclonal antibody against APLP2. This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
| Target |
APLP2 |
| Reactivity |
Human, Mouse |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human APLP2. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 59 kDa/79 kDa/80 kDa/85 kDa/86 kDa/87 kDa
Observed MW: 64 kDa |
| Swiss Prot |
Q06481
|
| GeneID |
334
|
| Gene Symbol |
APLP2 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
