24-Dehydrocholesterol Reductase (DHCR24) Antibody
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產(chǎn)品名稱(chēng): 24-Dehydrocholesterol Reductase (DHCR24) Antibody
產(chǎn)品型號(hào): abx004137
產(chǎn)品展商: 其他品牌
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24-Dehydrocholesterol Reductase (DHCR24) Antibody
24-Dehydrocholesterol Reductase (DHCR24) Antibody
的詳細(xì)介紹
DHCR24 Antibody is a Rabbit Polyclonal antibody against DHCR24. This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
| Target |
DHCR24 |
| Reactivity |
Human, Mouse |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human DHCR24. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 54 kDa/60 kDa
Observed MW: 55 kDa |
| Swiss Prot |
Q15392
|
| GeneID |
1718
|
| Gene Symbol |
DHCR24 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
