2'-5'-Oligoadenylate Synthetase 3 (OAS3) Antibody
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產(chǎn)品名稱: 2'-5'-Oligoadenylate Synthetase 3 (OAS3) Antibody
產(chǎn)品型號(hào): abx032743
產(chǎn)品展商: 其他品牌
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簡(jiǎn)單介紹
2'-5'-Oligoadenylate Synthetase 3 (OAS3) Antibody
2'-5'-Oligoadenylate Synthetase 3 (OAS3) Antibody
的詳細(xì)介紹
OAS3 is an interferon inducible protein that belongs to the 2-5A synthetase family, may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2', 5'-oligoadenylate molecules. GTP can be an alternative substrate. OAS3 binds double-stranded RNA and polymerizes ATP into PPP (A2'P5'A) N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. The protein is present at high level in placenta trophoblast.
| Target |
2'-5'-Oligoadenylate Synthetase 3 (OAS3) |
| Reactivity |
Human |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Human OAS3. |
| Purification |
Purified Rabbit Polyclonal Antibody. |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Specificity |
This OAS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1056-1087 amino acids from the C-terminal region of human OAS3. |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
Q9Y6K5
|
| Buffer |
PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
