Recombinant Human RANTES (CCL5)
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產(chǎn)品名稱: Recombinant Human RANTES (CCL5)
產(chǎn)品型號: Z100789
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關文檔
簡單介紹
Recombinant Human RANTES (CCL5)
Recombinant Human RANTES (CCL5)
的詳細介紹
|
Print Version |
| Alternative Names |
Regulation upon Activation Normal T cell Express Sequence, CCL5, SIS-delta, C-C motif chemokine 5, EoCP, Eosinophil chemotactic cytokine, Small-inducible cytokine A5, T cell-specific protein P228, TCP228, T-cell-specific protein RANTES, D17S136E, SCYA5 |
| Description |
RANTES belongs to the family of chemotactic cytokines known as chemokines and is expressed by an early response gene. The synthesis of RANTES is induced by TNF-alpha and IL-1-alpha. RANTES is chemotactic for T cells, human eosinophils and basophils and plays an active role in recruiting leukocytes into inflammatory sites. RANTES also activates eosinophils to release eosinophilic cationic protein while being a potent activator of oxidative metabolism specific for eosinophils. RANTES increases the adherence of monocytes to endothelial cells and selectively supports the migration of monocytes and T lymphocytes expressing the cell surface markers CD4 and UCHL1. |
| Gene Symbol |
CCL5 |
| Gene ID |
6352 |
| Accession No. |
P13501 |
| Source |
E. coli |
| Appearance |
Lyophilized Powder |
| Molecular Weight |
9.0 kDa |
| Endotoxin Level |
<1.0 EU/μg of recombinant protein as determined by the LAL method |
| Purity |
>95% as determined by SDS-PAGE |
| Gel Image |
 |
| Bioactivity |
Determined by its ability to chemoattract human blood monocytes using a concentration range of 1-10 ng/mL. |
| Bioactivity Data |
 |
| Formulation |
Lyophilized from a 0.2 μm filtered solution in PBS |
| Reconstitution |
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage |
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage |
For research use only. Not for diagnostic or therapeutic use. |
