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產(chǎn)品名稱: Recombinant Mouse IL25
產(chǎn)品型號(hào): Z200255
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡(jiǎn)單介紹
Recombinant Mouse IL25
Recombinant Mouse IL25
的詳細(xì)介紹
|
Print Version |
| Alternative Names |
UPF0556 protein, IL-25, Stromal cell-derived growth factor SF20, D17Wsu104e, Il25
Recombinant Mouse Interleukin-25 (IL25) |
| Description |
IL-25 (also known as IL- 17E), a member of the IL-17 family, has been implicated in Th2 cell-mediated immunity. Recently, IL-25 has been identified as one of the initiators of the Th2 response (10, 11) and has also been shown to be expressed by mast cells. The transgenic overexpression of IL-25 by lung epithelial cells results in mucus hyperproduction and airway infiltration of macrophages and eosinophils; conversely, IL-25 blockade reduced airway inflammation and Th2 cytokine production in an allergen-induced asthma model. |
| Gene Symbol |
IL25 |
| Gene ID |
140806 |
| Accession No. |
Q9CPT4 |
| Source |
E. coli |
| Appearance |
Lyophilized Powder |
| Molecular Weight |
16.0 kDa |
| Endotoxin Level |
<1.0 EU/μg of recombinant protein as determined by the LAL method |
| Purity |
>95% as determined by SDS-PAGE |
| Gel Image |
 |
| Bioactivity |
The ED(50) was determined by the dose-dependent proliferation of human umbilical vein endothelial cells and was found to be <0.5ng/mL. |
| Bioactivity Data |
 |
| Formulation |
Lyophilized from 0.2μm filtered solution in Tris and NaCl |
| Reconstitution |
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage |
Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.
Avoid repeated freeze/thaw cycles. |
| Usage |
For research use only. Not for diagnostic or therapeutic use. |
